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Determitation of Carbon, Nitrogen and Hydrogen in medicines

MonPM+07E_December+0700RDecPM+07_+07+07:0004
Created: 06 December 2021

Instrument: ECS 8020

Active principles and excipients studies are always on going in order to improve performances and minimize the side effects on human body. The studies involve the characterization of molecules and their reactions or interactions. There are several techniques used for these aims, ranging from different chemical, physical and biological analyses.

The elemental analysis is one of the basic technique involved in chemical structure investigations or interaction with other molecules, functionalization of functional groups and production processes. One of the most common application is the determination of elements like carbon, nitrogen and hydrogen to be compared to the designed chemical structure.

ECS8020 demonstrated a perfect attitude in medicines analysis.

 

Sample

Carbon

Nitrogen

Hydrogen

Ibuprofen based

46.1±0.5

6.45±0.27

6.77±0.01

Ketoprofen based

41.3±0.1

1.07±0.01

7.7±0

Average accuracy

0.73

2.4

0.05

All reported values unit: %

     

 

medi1

 

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